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TRT + GLP-1 Recomposition Started on Oct 16, 2026 • 38,490 views • 4 replies

Running TRT ($99/mo) + Compounded Tirzepatide ($99/mo) Together: Ultimate Men's Over-40 Body Recomposition Stack?

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shaun_lifting_44 Thread Starter
Joined Jan 2025 • 67 posts
#1
Oct 16, 2026

Wanted to share my 16-week lab and DEXA results running optimized Testosterone Cypionate (150mg/wk via Peter MD at $99/mo) combined with Compounded Tirzepatide (5mg/wk via Telehealth FX 503A at $99/mo). Starting stats at age 44: 238 lbs, 29.4% body fat, Total T 335 ng/dL, A1c 5.9%. Week 16 stats: 199 lbs (-39 lbs scale weight), body fat dropped to 14.8%, and I actually GAINED 3.2 lbs of lean skeletal muscle on DEXA while in a deficit! Total cost for both protocols combined is under $200/mo.

Community Replies (4)

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Dr_Aris_Endo Clinical Researcher
Joined Nov 2023 • 740 posts
#2
Oct 17, 2026

Biochemically, TRT + Tirzepatide is the gold standard for male metabolic syndrome. Visceral adipose tissue expresses high levels of aromatase, which converts endogenous testosterone into estradiol. As Tirzepatide strips away visceral fat and lowers fasting insulin, aromatase activity plummets, while physiological TRT locks in positive nitrogen balance so 95%+ of weight lost comes strictly from adipose tissue rather than skeletal muscle.

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Rob_M_Houston Verified Patient
Joined Apr 2025 • 49 posts
#3
Oct 20, 2026

Running this exact $99 Tirzepatide + $99 Peter MD TRT combo right now. Down 34 lbs around my waist, bench press is actually up 20 lbs, and my blood pressure went from 138/88 to 116/74.

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shaun_lifting_44 Thread Starter
Joined Jan 2025 • 68 posts
#5
Nov 04, 2026

Week 18 update: 195 lbs even, abs visible for the first time since college, and paying $198/mo combined for both medical protocols.

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Have you used this telehealth protocol or switched pharmacies in 2026?

$99/mo Tirzepatide → $99/mo Men's TRT →